Environmentally azithromycin pharmaceutical wastewater management and synergetic biocompatible approaches of loaded azithromycin@hematite nanoparticles환경적으로 아지스로마이신 제약 폐수 관리 및 로딩된 아지트로마이신@적철석 나노입자의 상승적 생체 적합성 접근법Article Published on 2022-06-292022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] activity Adsorption adsorption capacity Antibacterial antibacterial activity antibiotic anticancer Antiviral antiviral activities antiviral activity approach approach Azithromycin Bacteria biosynthesized Cancer cell line Concentration condition conducted contaminant Contamination COVID-19 virus cytotoxicity described dose Echinacea experiments gram Gram-negative bacteria Hematite HepG2 investigated isothermal kinetic Kinetics Langmuir model management manifested parameter pharmaceutical platform R 2 removal reported SARS-CoV-2 strain synergistic synergistic effect therapeutic therapeutic index thermodynamic Treatment virus [DOI] 10.1038/s41598-022-14997-y PMC 바로가기 [Article Type] Article
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics녹농균(Pseudomonas aeruginosa): 병인, 독성 인자, 항생제 내성, 숙주와의 상호 작용, 기술 발전 및 새로운 치료법Review Published on 2022-06-252022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 유전자 메커니즘, [키워드] addition Antibiotic resistance Antibiotics antimicrobial autophagy Bacterial Bacterial pathogenesis bioinformatics burn wounds Cancer caused Cell signaling cGAS chronic obstructive clinically COPD COVID-19 CRISPR CRISPR-Ca cystic fibrosis Defense develop disorder drug drug resistance Drug screening effective effort Factor Factors fibrosis gram Host host defense host immune responses host-pathogen interaction immune immune responses immunodeficiency IMPROVE infect Infection infections Inflammasome Interaction intractable invasive LPS mammalian cell mechanism metabolomics molecular Non-coding RNAs opportunistic pathogen outer membrane P. aeruginosa pathogen Pathogenesis Pathways Patient platform Pseudomona Pseudomonas aeruginosa rapid progress Regulation Research scRNA-seq secretion Severe infection signaling pathways Strains therapy traits treat use of antibiotics Ventilation Vesicle virulence widespread [DOI] 10.1038/s41392-022-01056-1 PMC 바로가기 [Article Type] Review
Six Feet under Microbiota: Microbiologic Contamination and Toxicity Profile in Three Urban Cemeteries from Lisbon, Portugal미생물총 아래 6피트: 포르투갈 리스본의 3개 도시 공동묘지의 미생물학적 오염 및 독성 프로파일Article Published on 2022-05-162022-09-11 Journal: Toxins [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] A549 Analysis Aspergillus azole azole resistance Bacteria cemeteries Cemetery conducted Contamination cytotoxic cytotoxic effects cytotoxicity EDC Effect electrostatic environmental reservoir epithelial cells Future gram Gram-negative bacteria Health HepG2 HepG2 cells highest Lung epithelial cells management Measures media microbial molecular mycophenolic acid mycotoxins occupational health occupational health. organic matter pathogenic microorganism Pathogenic microorganisms Portugal profile ranged reached risk Risk management SARS-CoV-2 swabs Total urban [DOI] 10.3390/toxins14050348 PMC 바로가기 [Article Type] Article
Secondary infection in COVID-19 critically ill patients: a retrospective single-center evaluationCOVID-19 중환자 환자의 2 차 감염 : 후 향적 단일 센터 평가Observational Study Published on 2022-03-022022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 임상, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus administration of corticosteroid Admission adult COVID-19 patient aggravate Bacteremia Bacterial infection Bacterial infections Belgium bloodstream infection Bloodstream infections catheter caused cocci Combination coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients Culture cultures cumulative Cumulative Dose database develop diabetes Diabetes Mellitus dose eligible for inclusion Gender gram group higher risk highest ICU identify Immunosuppression incidence increased risk Infection intensive care intensive care unit Observational cohort study pathogen Pathogens Patient patients Pneumonia proportion Research Result resulting retrospective retrospective observational cohort study risk risk factor risk of death SARS-CoV-2 secondary bacterial infection Secondary bacterial infections Secondary infection secondary infections secondary pneumonia Sepsis severe acute respiratory syndrome Coronavirus severity severity of illness single-center supplementary material susceptible virus Virus Disease was performed [DOI] 10.1186/s12879-022-07192-x PMC 바로가기 [Article Type] Observational Study
Absence of YhdP, TamB, and YdbH leads to defects in glycerophospholipid transport and cell morphology in Gram-negative bacteriaYHDP, TAMB 및 YDBH의 부재는 그람 음성 박테리아에서 글리세로 포스 포스 폴리티드 수송 및 세포 형태의 결함으로 이어진다Research Article Published on 2022-02-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence accumulate adjust anterograde antibiotic Antibiotic resistance asymmetric Bacterial balance biosynthetic biosynthetic pathways Cell cell envelope cell lysis changes in characterized component contribute Critical Defense effective foundation gram Gram-negative bacteria homeostasis homologues inner leaflet leads lipopolysaccharide LPS maintain maintaining membrane membrane vesicles morphology mutant offer outer membrane overexpression pathway phenotype Phenotypes Protein provide reducing rescued restored sensitivity shedding the cell Therapies Threats translocated Transport understanding vesicles viability [DOI] 10.1371/journal.pgen.1010096 PMC 바로가기 [Article Type] Research Article
The changing pattern of bacterial and fungal respiratory isolates in patients with and without COVID-19 admitted to intensive care unitObservational Study Published on 2022-02-232022-10-04 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, [키워드] acute respiratory syndrome antibiotic Antimicrobial therapy Bacteria Bacterial BAL Bronchoalveolar lavage carbapenem collected Complete conducted contrary COVID-19 COVID-19 pandemic COVID-19 patients COVID-19 positive patient Effect Enterococcus evaluate First wave fungal gram Haemophilus influenzae hospital Hospitalization Hospitalized ICU ICUs increase in Intensive intensive care intensive care unit isolate isolates Italy national health system Nurse objective observé pandemic Patient patients with COVID-19 patients without COVID-19 Period Personal protective equipment positive Prevalence profile protocol Pseudomona reduction Result retrospective SARS-CoV-2 statistically significant Streptococcus pneumoniae Surveillance tertiary referral hospital tracheal [DOI] 10.1186/s12879-022-07176-x PMC 바로가기 [Article Type] Observational Study
Vaccine effectiveness against SARS-CoV-2 infection, hospitalization, and death when combining a first dose ChAdOx1 vaccine with a subsequent mRNA vaccine in Denmark: A nationwide population-based cohort studyObservational Study Published on 2021-12-172022-10-04 Journal: PLoS Medicine [Category] SARS, 임상, [키워드] 95% confidence interval adjusted age analysis calculate ChAdOx1 ChAdOx1 vaccine changed characterized CIs Combination Comorbidity confounder coronavirus 2 country covariate Coverage COVID-19 COVID-19 pandemic Cox regression model creating death Denmark distribution dose Effectiveness estimate events first dose follow-up time General population gram Heterologous heterologous vaccine Homologous vaccine Hospital admission Hospitalization Immunity individual individuals Infection knowledge limitation male median age Mie mRNA vaccine National outcomes Poisson population-based cohort previous study recommendation reduction in Registration registry data Research researcher respiratory risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine second dose Sex study period study population subsequent System vaccination Vaccine Vaccines was obtained were used [DOI] 10.1371/journal.pmed.1003874 PMC 바로가기 [Article Type] Observational Study
Transparent Polymeric Formulations Effective against SARS-CoV-2 InfectionSARS-CoV-2 감염에 효과적인 투명한 고분자 제제Article Published on 2021-11-242022-09-11 Journal: ACS applied materials & interfaces [Category] SARS, 치료제, [키워드] 229E alternative Antibacterial antibacterial activity antimicrobial agent antimicrobial agents Antiviral antiviral activity antiviral property approaches backbone Bacteria benzalkonium Candida albican Candida albicans candidate Cell CFU class Compound compounds Contact contaminated surface contaminated surfaces coronavirus decrease droplet droplets EMA European Medicines Agency evaluated Formulation fungal gram Gram-negative bacteria Gram-positive bacteria growth increasingly inhibit Ion Particle Polymer polymers polystyrene sulfonate Postinfection product reduction SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection SARS-CoV-2 virus silver silver. Spread sulfonate target cell tested the SARS-CoV-2 virus Transmission transmitted variety virucidal virus [DOI] 10.1021/acsami.1c10404 PMC 바로가기 [Article Type] Article
Comparison of post-cataract surgery endophthalmitis rates using syringing or regurgitation on pressure over the lacrimal sac as a preoperative screening tool for nasolacrimal duct obstruction: An impact assessment of protocol alteration due to the COVID-19 pandemic비루관 폐쇄에 대한 수술 전 선별 검사 도구로 누낭에 대한 압력에 대한 주사기 또는 역류를 사용한 백내장 수술 후 안내염 비율 비교: COVID-19 범유행으로 인한 프로토콜 변경의 영향 평가Article Published on 2021-10-012022-09-11 Journal: Indian journal of ophthalmology [Category] SARS, 치료기술, [키워드] Analysis anterior chamber Cataract cellular comparable Comparative analysis COVID-19 COVID-19 pandemic endophthalmitis eye eyes Final GRADE gram group haze hypopyon lacrimal sac organism PCE performed presenting pressure protocol regurgitation retrospective ROPLAS single-center syringing. two groups visual acuity vitreous was performed [DOI] 10.4103/ijo.IJO_1218_21 PMC 바로가기 [Article Type] Article
Photocatalytic Treatments for Personal Protective Equipment: Experimental Microbiological Investigations and Perspectives for the Enhancement of Antimicrobial Activity by Micrometric TiO 2Article Published on 2021-08-162022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] A significant reduction acquisition activated activity addition antimicrobial Bacteria Contagion country COVID-19 pandemic Disinfection droplet E. coli Efficacy enhancement equipment facial gram IMPROVE individual investigation Mask microbial Nanoparticles Personal protective equipment Photocatalysis positive PPE Prevent problems Radiation reduce reuse Support Suspension titanium dioxide wavelengths [DOI] 10.3390/ijerph18168662 PMC 바로가기 [Article Type] Article